Signs and symptoms include: Generalized urticaria (hives) or widespread pruritic rash Angioedema affecting the face, lips, tongue, or throat Respiratory symptoms including wheezing, dyspnea, or throat tightness Gastrointestinal symptoms such as severe abdominal cramping, nausea, or vomiting (distinct from common GI side effects) Cardiovascular manifestations including tachycardia, hypotension, or dizziness Anaphylaxis represents the most severe form of allergic reaction and constitutes a medical emergency
AstraZeneca AB., Stockholm Sweden
, Baker, D
Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS) Healthcare providers are strongly encouraged to complete a REMS compliant education program and to counsel patients and caregivers on serious risks, safe use, and the importance of reading the Medication Guide with each prescription (see WARNINGS)
IGF-1 DES was originally researched for medical uses, including: Muscle wasting diseases Cachexia Injury rehabilitation Recovery from surgery Support in aging-related muscle loss The goal was to harness IGF-1s anabolic and regenerative potential while reducing systemic effects and controlling the location of its action